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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-3
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pubmed:dateCreated |
1997-2-10
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pubmed:abstractText |
The B2-bradykinin receptor gene has been proposed as one of the candidate genes involved in the complex genetic underpinnings of common chronic disorders such as hypertension, ischemic heart disease or allergic asthma. Suitable genetic markers are needed to study these hypotheses. Therefore, it was our aim to identify polymorphic sites in the B2-receptor gene. Up to now, we characterized four polymorphisms: one in the promoter region and three other ones in each of the exons. Possible biological consequences are delineated and preliminary results of allele specific different biological action are shown.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0162-3109
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8856111-Alleles,
pubmed-meshheading:8856111-Asthma,
pubmed-meshheading:8856111-Base Sequence,
pubmed-meshheading:8856111-Cell Line,
pubmed-meshheading:8856111-DNA Primers,
pubmed-meshheading:8856111-Gene Frequency,
pubmed-meshheading:8856111-Humans,
pubmed-meshheading:8856111-Hypertension,
pubmed-meshheading:8856111-Myocardial Ischemia,
pubmed-meshheading:8856111-Polymerase Chain Reaction,
pubmed-meshheading:8856111-Polymorphism, Genetic,
pubmed-meshheading:8856111-Receptor, Bradykinin B2,
pubmed-meshheading:8856111-Receptors, Bradykinin,
pubmed-meshheading:8856111-Risk Factors,
pubmed-meshheading:8856111-Transfection
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pubmed:year |
1996
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pubmed:articleTitle |
Polymorphisms in the gene for the human B2-bradykinin receptor. New tools in assessing a genetic risk for bradykinin-associated diseases.
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pubmed:affiliation |
Children's Hospital, Department of Clinical Chemistry and Biochemistry, University of Munich, Germany.
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pubmed:publicationType |
Journal Article
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