Linked Life Data

8851296

Source:http://linkedlifedata.com/resource/pubmed/id/8851296

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-12-16
pubmed:abstractText
In a controlled prospective study we used peripheral autonomic surface potentials (PASP) and an autonomic test battery (valsalva, 30:15 ratio, deep breathing, sustained handgrip, Schellong test) to evaluate HIV-1 associated autonomic dysfunction (HIVAD) in 38 HIV-seropositive patients. Criteria of exclusion were drug or alcohol abuse, concurrent infections, neoplasms, wasting syndrome and neurotoxic medication. We found increased PASP onset latencies and lower PASP amplitudes even in asymptomatic HIV-infected patients (p < 0.0125, Bonferroni corrected p-value). A mild or marked HIVAD was detected in 21% of the patients each. Heart rate and blood pressure responses were similarly affected. HIVAD was not related to HIV-1 associated changes in sural and tibial nerve conduction parameters. Our data suggest that HIVAD is a frequent complication of HIV-1 infection and that HIV-1 plays a direct role in its pathogenesis. Sympathetic and parasympathetic divisions of the ANS appear to be similarly affected.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0028-2804
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-54
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
[HIV-1 associated autonomic dysfunction (HIVAD)].
pubmed:affiliation
Neurologische Universitätsklinik, Essen.
pubmed:publicationType
Journal Article, English Abstract