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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-12-9
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pubmed:abstractText |
Leukoplakia, a white patch in the oral cavity or in the larynx that cannot be scraped off is a premalignant precursor of squamous cell carcinoma. It is tobacco-related and easily monitored. The rate of transformation of leukoplakia into invasive cancer is directly related to the degree of histologic abnormality. In the largest and longest study in the United States (mean follow-up, 7.2 years), the long-term transformation rate for dysplastic lesions was 36%. Surgical removal is considered the best therapy. However many patients operated on for oral leukoplakia later develop local relapses, new leukoplakias, or squamous cell carcinoma. Although leukoplakia lesions can show spontaneous regression, the response rate observed under treatment of retinoids is much greater.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0935-8943
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-33
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8851116-Aged,
pubmed-meshheading:8851116-Aged, 80 and over,
pubmed-meshheading:8851116-Anticarcinogenic Agents,
pubmed-meshheading:8851116-Cell Transformation, Neoplastic,
pubmed-meshheading:8851116-Dose-Response Relationship, Drug,
pubmed-meshheading:8851116-Drug Administration Schedule,
pubmed-meshheading:8851116-Female,
pubmed-meshheading:8851116-Humans,
pubmed-meshheading:8851116-Laryngeal Neoplasms,
pubmed-meshheading:8851116-Larynx,
pubmed-meshheading:8851116-Leukoplakia,
pubmed-meshheading:8851116-Male,
pubmed-meshheading:8851116-Middle Aged,
pubmed-meshheading:8851116-Vitamin A
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pubmed:year |
1996
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pubmed:articleTitle |
[High concentrate A-mulsin, a new therapy concept in laryngeal leukoplakia].
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pubmed:affiliation |
Klinik und Poliklinik für Hals-, Nasen-, Ohrenkranke, Universität München.
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pubmed:publicationType |
Journal Article,
English Abstract
|