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rdf:type |
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lifeskim:mentions |
umls-concept:C0015576,
umls-concept:C0020792,
umls-concept:C0025268,
umls-concept:C0026882,
umls-concept:C0205160,
umls-concept:C0205557,
umls-concept:C0430136,
umls-concept:C0543431,
umls-concept:C0680022,
umls-concept:C0694890,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
2
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pubmed:dateCreated |
1997-1-2
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|
pubmed:abstractText |
The pentagastrin stimulation test is the traditional test used for the identification of asymptomatic individuals in multiple endocrine neoplasia type 2A (MEN 2A) and familial medullary thyroid carcinoma (FMTC). The identification of mutations in the RET proto-oncogene segregating with the disease phenotype in MEN 2A and FMTC families has made it possible to re-examine the validity of using this test for the identification of affected family members.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0300-0664
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pubmed:author |
pubmed-author:AndrewS DSD,
pubmed-author:Clifton-BlighPP,
pubmed-author:DelbridgeLL,
pubmed-author:DiamondTT,
pubmed-author:GaskinE LEL,
pubmed-author:HylandV JVJ,
pubmed-author:MarshD JDJ,
pubmed-author:McDowallDD,
pubmed-author:NevellD FDF,
pubmed-author:RobinsonB GBG,
pubmed-author:SchnitzlerMM
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-20
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8849577-Adolescent,
pubmed-meshheading:8849577-Adult,
pubmed-meshheading:8849577-Calcitonin,
pubmed-meshheading:8849577-Carcinoma, Medullary,
pubmed-meshheading:8849577-Child,
pubmed-meshheading:8849577-DNA Mutational Analysis,
pubmed-meshheading:8849577-Drosophila Proteins,
pubmed-meshheading:8849577-False Positive Reactions,
pubmed-meshheading:8849577-Female,
pubmed-meshheading:8849577-Humans,
pubmed-meshheading:8849577-Hyperplasia,
pubmed-meshheading:8849577-Male,
pubmed-meshheading:8849577-Multiple Endocrine Neoplasia Type 2a,
pubmed-meshheading:8849577-Pedigree,
pubmed-meshheading:8849577-Pentagastrin,
pubmed-meshheading:8849577-Proto-Oncogene Proteins,
pubmed-meshheading:8849577-Proto-Oncogene Proteins c-ret,
pubmed-meshheading:8849577-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:8849577-Thyroid Gland,
pubmed-meshheading:8849577-Thyroid Neoplasms
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pubmed:year |
1996
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pubmed:articleTitle |
The identification of false positive responses to the pentagastrin stimulation test in RET mutation negative members of MEN 2A families.
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pubmed:affiliation |
Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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