Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 Pt 1
pubmed:dateCreated
1996-10-24
pubmed:abstractText
Premature infants are susceptible to disease related to deficient dietary calcium intake. Studies in adults suggest carbohydrates can enhance calcium absorption. However, little is known about how carbohydrates affect calcium absorption in premature infants due to a lack of direct in vivo studies. We adapted the triple lumen perfusion method for use in premature infants to compare calcium absorption 36 mmol/L (1.44 g/L) in the absence and presence of either 70 g/L lactose or glucose polymers. 44Ca was added to determine endogenous calcium losses. Fourteen infants were studied (gestational age: 31 +/- 0.4 wk; study weight: 1590 +/- 105 g; mean +/- SEM). Calcium absorption from the glucose polymer solution was greater than that from the control and lactose solutions (0.17 +/- 0.05 mumol.min-1.cm-1 versus 0.04 +/- 0.04 and 0.008 +/- 0.045 mumol.min-1.cm-1, respectively). Calcium absorption correlated positively with water and carbohydrate absorption. The rate of carbohydrate absorption was greater from the glucose polymers than from the lactose solution (0.40 +/- 0.10 mg.min-1.cm-1 versus 0.22 +/- 0.06, respectively). Based upon 44Ca absorption, endogenous calcium loss appeared to account for less than 1% of total calcium flux. We conclude that glucose polymers, but not lactose, enhance calcium absorption in the premature infant, a fact that may be useful in formula design.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0031-3998
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
666-70
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Effect of carbohydrates on calcium absorption in premature infants.
pubmed:affiliation
USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't