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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3 Suppl
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pubmed:dateCreated |
1977-9-29
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pubmed:abstractText |
Forty patients with a mean age of 65 years (range 44-76 years) were operated on; 30 of 40 patients (75%) had prior myocardial infarction. All had severe therapy-resistant congestive heart failure, 75% (30 of 40 patients) were symptomatic at rest, and 25% (10 of 40 patients) were symptomatic on minimal exertion. Cardiac index ranged from 1.24-2.84 L/min/m2 (mean 1.99). Left ventricular end-diastolic pressure ranged from 3-36 mm Hg (mean 18). All patients had significant mitral insufficiency and contractility was reduced markedly to moderately in 63% (25 of 40 patients). Significant coronary artery disease (obstruction greater than or equal to 75%) was present in all patients. All had mitral valve replacement, 30 had bypass surgery, and 7 left ventricular aneurysmectomy. Five died during surgery or before discharge (early mortality 12.5%). After a mean follow-up period of 16 months, another eight patients died, two with causes not related to the cardiovascular system (total mortality 32.5%). Of 20 patients with a cardiac index greater than or equal to 1.5 L/min/m2 and an ejection fraction greater than or equal to 0.40, 17 survived surgery and improved postoperatively. Mitral valve replacement for this group of patients is recommended.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0009-7322
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
II101-4
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:884813-Adult,
pubmed-meshheading:884813-Aged,
pubmed-meshheading:884813-Animals,
pubmed-meshheading:884813-Cardiac Output,
pubmed-meshheading:884813-Female,
pubmed-meshheading:884813-Heart Failure,
pubmed-meshheading:884813-Heart Valve Prosthesis,
pubmed-meshheading:884813-Humans,
pubmed-meshheading:884813-Male,
pubmed-meshheading:884813-Middle Aged,
pubmed-meshheading:884813-Mitral Valve,
pubmed-meshheading:884813-Myocardial Contraction,
pubmed-meshheading:884813-Myocardial Revascularization,
pubmed-meshheading:884813-Papillary Muscles,
pubmed-meshheading:884813-Swine,
pubmed-meshheading:884813-Transplantation, Heterologous
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pubmed:year |
1977
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pubmed:articleTitle |
Mitral valve replacement in medically unresponsive congestive heart failure due to papillary muscle dysfunction.
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pubmed:publicationType |
Journal Article
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