pubmed-article:8847707 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8847707 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
pubmed-article:8847707 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
pubmed-article:8847707 | lifeskim:mentions | umls-concept:C0205312 | lld:lifeskim |
pubmed-article:8847707 | lifeskim:mentions | umls-concept:C0001047 | lld:lifeskim |
pubmed-article:8847707 | lifeskim:mentions | umls-concept:C0008405 | lld:lifeskim |
pubmed-article:8847707 | lifeskim:mentions | umls-concept:C0243126 | lld:lifeskim |
pubmed-article:8847707 | pubmed:issue | 5 | lld:pubmed |
pubmed-article:8847707 | pubmed:dateCreated | 1996-10-24 | lld:pubmed |
pubmed-article:8847707 | pubmed:abstractText | The role of regenerative processes in the protective effect of N-acetyl-L-cysteine (NAC) against bromoethylamine-induced renal papillary necrosis was assessed in rats given bromoethylamine (BEA)(1.2 mmol/kg), N-acetylcysteine (6 mmol/kg), or N-acetyl-cysteine plus BEA. Renal papillary slices were dissected after 15 hours of treatment, and 14C-choline incorporation into total phospholipid, lysophosphatidylcholine, sphingomyelin, and phosphatidylcholine was measured. Bromoethylamine elicited an increase in the incorporation of 14C-choline into choline-containing phospholipid, an effect that was abolished when N-acetylcysteine was administered prior to bromoethylamine. These studies indicate that the defensive mechanism of N-acetylcysteine against bromoethylamine-induced renal papillary necrosis is not related to regenerative processes and that N-acetylcysteine abolishes the bromoethylamine-induced choline incorporation into papillary phospholipid. | lld:pubmed |
pubmed-article:8847707 | pubmed:language | eng | lld:pubmed |
pubmed-article:8847707 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8847707 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8847707 | pubmed:month | Oct | lld:pubmed |
pubmed-article:8847707 | pubmed:issn | 0887-2082 | lld:pubmed |
pubmed-article:8847707 | pubmed:author | pubmed-author:VidelaL ALA | lld:pubmed |
pubmed-article:8847707 | pubmed:author | pubmed-author:RosenblumNN | lld:pubmed |
pubmed-article:8847707 | pubmed:author | pubmed-author:ThielemannL... | lld:pubmed |
pubmed-article:8847707 | pubmed:author | pubmed-author:OberhauserE... | lld:pubmed |
pubmed-article:8847707 | pubmed:author | pubmed-author:RodrigoR ARA | lld:pubmed |
pubmed-article:8847707 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8847707 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:8847707 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8847707 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8847707 | pubmed:pagination | 251-257 | lld:pubmed |
pubmed-article:8847707 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:8847707 | pubmed:meshHeading | pubmed-meshheading:8847707-... | lld:pubmed |
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pubmed-article:8847707 | pubmed:meshHeading | pubmed-meshheading:8847707-... | lld:pubmed |
pubmed-article:8847707 | pubmed:year | 1995 | lld:pubmed |
pubmed-article:8847707 | pubmed:articleTitle | N-acetyl-L-cysteine abolishes the bromoethylamine-induced choline incorporation into renal papillary tissue. | lld:pubmed |
pubmed-article:8847707 | pubmed:affiliation | Departamento de Medicina Experimental, Universidad de Chile, Santiago. | lld:pubmed |
pubmed-article:8847707 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8847707 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |