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pubmed-article:8847528pubmed:abstractTextAmino acid residues 81-100 of the hepatitis C virus (HCV) nucleoprotein contain a cytotoxic T cell epitope that is recognized by cytotoxic T lymphocytes (CTLs) in association with human leukocyte antigen B44. With panels of truncated and overlapping peptides, the minimal and optimal epitope recognized by CTLs was shown to be a 9-mer peptide (residues 88-96). The peptide can stimulate effectively CTLs that are able to recognize endogenously synthesized and processed HCV nucleoprotein.lld:pubmed
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pubmed-article:8847528pubmed:articleTitleA minimal and optimal cytotoxic T cell epitope within hepatitis C virus nucleoprotein.lld:pubmed
pubmed-article:8847528pubmed:affiliationThird Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.lld:pubmed
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