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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1996-10-24
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pubmed:abstractText |
Effects of propofol (12.5 mg kg-1, i.v. bolus injection) or 0.9% sodium chloride on arterial blood pressure, arterial blood gases and hepatic circulation (radio-labelled microsphere technique) were studied in 15 conscious and unpremedicated rabbits. No significant changes were observed after sodium chloride. Propofol resulted in anaesthesia, respiratory depression (-49 +/- 14% decrease in PaO2; mean +/- SD) and hypotension (-49 +/- 13% decrease in mean arterial pressure; mean +/- SD) but no changes in hepatic arterial and portal venous blood flows. We conclude that propofol does not affect the liver circulation despite marked depression of mean arterial pressure and respiration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0144-5979
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
515-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8846671-Anesthesia,
pubmed-meshheading:8846671-Animals,
pubmed-meshheading:8846671-Blood Flow Velocity,
pubmed-meshheading:8846671-Blood Gas Analysis,
pubmed-meshheading:8846671-Blood Pressure,
pubmed-meshheading:8846671-Liver,
pubmed-meshheading:8846671-Propofol,
pubmed-meshheading:8846671-Rabbits,
pubmed-meshheading:8846671-Radioligand Assay,
pubmed-meshheading:8846671-Time Factors
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pubmed:year |
1995
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pubmed:articleTitle |
Induction of anaesthesia by propofol and hepatic blood flow in the rabbit.
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pubmed:affiliation |
Département d'Anesthésie-Réanimation Chirurgicale, Hôtel-Dieu, Nantes, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|