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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-11-18
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pubmed:abstractText |
The diagnostic value of a new tumor marker, CYFRA 21-1, was studied in the blood samples collected from 22 controls, and 87 pre-treatment patients with squamous cell carcinoma of the cervix. Sensitivity and specificity of CYFRA 21-1 was compared with those of squamous cell carcinoma antigen (SCC) measured in the sera of the same patients. Serum CYFRA 21-1 levels were higher in patients with squamous cell carcinoma than in controls (p < 0.05), and correlated with FIGO stage (Stage IIb-IV vs. Stage Ib-IIa, p = 0.0477). Using 2.5 ng/ml as cut-off value, elevated CYFRA 21-1 levels were found in 13.6% of controls, 34.8% of patients with Stage Ib-IIa squamous cell carcinoma of the cervix, and 63.5% of patients with Stage IIb-IV squamous cell carcinoma of the cervix. However, there was less sensitivity and specificity of CYFRA 21-1 than those of SCC in detecting squamous cell carcinoma of the cervix. CYFRA 21-1 may not be a better tumor marker than SCC for squamous cell carcinoma of the cervix.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Serpins,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/squamous cell carcinoma-related...
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pubmed:status |
MEDLINE
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pubmed:issn |
0028-2685
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8843956-Aged,
pubmed-meshheading:8843956-Antigens, Neoplasm,
pubmed-meshheading:8843956-Carcinoma, Squamous Cell,
pubmed-meshheading:8843956-Female,
pubmed-meshheading:8843956-Humans,
pubmed-meshheading:8843956-Keratins,
pubmed-meshheading:8843956-Middle Aged,
pubmed-meshheading:8843956-Peptide Fragments,
pubmed-meshheading:8843956-Reference Values,
pubmed-meshheading:8843956-Serpins,
pubmed-meshheading:8843956-Tumor Markers, Biological,
pubmed-meshheading:8843956-Uterine Cervical Neoplasms
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pubmed:year |
1996
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pubmed:articleTitle |
Study of a new tumor marker, CYFRA 21-1, in squamous cell carcinoma of the cervix, and comparison with squamous cell carcinoma antigen.
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pubmed:affiliation |
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, R.O.C.
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pubmed:publicationType |
Journal Article,
Comparative Study
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