Linked Life Data

8843605

Source:http://linkedlifedata.com/resource/pubmed/id/8843605

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1996-12-30
pubmed:abstractText
Optic nerves, like other CNS tracts, consist of axons closely apposed across narrow extracellular clefts to the cell bodies and processes of glial cells. Despite the anatomical simplicity of these pathways and the absence of synapses, a surprising range of interactions occurs between axons and glial cells mediated by changes in the chemical composition of the extracellular fluid produced by glial or neuronal stimulation. Some of the interactions are relatively brief, resulting from alterations in extracellular ions such as K+ or H+, or alterations of small molecules like glutamate or ATP. Other interactions involve much longer time periods and presumably larger signaling molecules, like peptides or proteins. These play a role not only in the development of axonal pathways but also in the processes of degeneration and regeneration that follow brain injury or disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0166-2236
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
352-8
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Glial-neuronal interactions in non-synaptic areas of the brain: studies in the optic nerve.
pubmed:affiliation
Dept of Neurology, University of Washington School of Medicine, Seattle 98195-6465, USA.
pubmed:publicationType
Journal Article, Review