Linked Life Data

8843367

Source:http://linkedlifedata.com/resource/pubmed/id/8843367

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-12-10
pubmed:abstractText
Image-guided, single voxel, localized proton magnetic resonance (MR) spectroscopy was performed to assess the brain metabolite changes in 10 (n = 10) alcoholic patients in the frontal lobe, cerebellum, and thalamus regions. The spectra obtained were characterized by a reduced N-acetyl-aspartate (NAA) to choline (Cho) (p < .01) and NAA to total creatine (Cr + PCr) (p < .01) ratios relative to age-matched (n = 27) controls. These decreased ratios correspond to depleted concentration of the metabolite levels such as NAA and Cho. Reduction of NAA is consistent with the neuronal loss while reduction in Cho suggests significant changes in the membrane lipids of alcoholics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0730-725X
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
553-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Brain metabolite changes in alcoholism: an in vivo proton magnetic resonance spectroscopy (MRS) study.
pubmed:affiliation
Department of N.M.R., All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
pubmed:publicationType
Journal Article