Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-12-24
pubmed:abstractText
In a randomized double-blind study 60 children, undergoing the extraction of carious deciduous teeth under day-case general anaesthesia, were assigned to receive either intravenous nalbuphine hydrochloride 0.3 mg kg-1 (n = 21), one or more diclofenac suppositories 12.5 mg to a dose of 1-2 mg kg-1 (n = 19), or no analgesia (n = 20). The duration of anaesthesia was longer in the diclofenac group (9.6 min, SD 3.5) compared with control (7.2 min, SD 2.6) and nalbuphine (6.9 min, SD 3.0) groups respectively (P < 0.05). There were no statistically significant differences in post-operative pain scores during the 45 min post-operative period studied between the three groups using an objective pain score. We conclude that using this methodology we were unable to demonstrate any statistically significant differences between the analgesic effects of either intravenous (i.v.) nalbuphine or diclofenac suppositories compared with control.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0265-0215
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:8842656-Acetaminophen, pubmed-meshheading:8842656-Administration, Rectal, pubmed-meshheading:8842656-Ambulatory Surgical Procedures, pubmed-meshheading:8842656-Analgesics, Non-Narcotic, pubmed-meshheading:8842656-Analgesics, Opioid, pubmed-meshheading:8842656-Anesthesia, Dental, pubmed-meshheading:8842656-Anesthesia, General, pubmed-meshheading:8842656-Anti-Inflammatory Agents, Non-Steroidal, pubmed-meshheading:8842656-Child, pubmed-meshheading:8842656-Child, Preschool, pubmed-meshheading:8842656-Child Behavior, pubmed-meshheading:8842656-Dental Caries, pubmed-meshheading:8842656-Diclofenac, pubmed-meshheading:8842656-Double-Blind Method, pubmed-meshheading:8842656-Female, pubmed-meshheading:8842656-Humans, pubmed-meshheading:8842656-Injections, Intravenous, pubmed-meshheading:8842656-Male, pubmed-meshheading:8842656-Nalbuphine, pubmed-meshheading:8842656-Pain, Postoperative, pubmed-meshheading:8842656-Suppositories, pubmed-meshheading:8842656-Time Factors, pubmed-meshheading:8842656-Tooth, Deciduous, pubmed-meshheading:8842656-Tooth Extraction
pubmed:year
1996
pubmed:articleTitle
Post-operative pain relief in children following extraction of carious deciduous teeth under general anaesthesia: a comparison of nalbuphine and diclofenac.
pubmed:affiliation
Anaesthetics Unit, London Hospital Medical College, Royal London Hospital, Whitechapel, UK.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial