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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1996-11-27
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pubmed:abstractText |
The aim of this study was to assess breathing patterns during sleep in patients with generalized mild myasthenia gravis. Fourteen patients (13 F; 1M, age range 20-40 years) in a stable clinical and functional state underwent a sleep questionnaire, baseline respiratory function tests and standard nocturnal polysomnography. All of the patients had normal daytime blood-gas values, except one who showed mild hypoxemia. No patient complained of disturbed sleep; six patients reported snoring. In five patients nocturnal polysomnography showed the occurrence of short and infrequent central apneas mainly during REM sleep, together with a drop in HbSaO2 levels of more than 5% of the baseline wakefulness value. Our data indicate that, in patients with mild generalized MG in a stable functional state, breathing pattern instability during sleep is infrequent and, when it occurs, is mild and mainly related to REM sleep.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0392-0461
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
589-94
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8838784-Adult,
pubmed-meshheading:8838784-Blood Gas Analysis,
pubmed-meshheading:8838784-Female,
pubmed-meshheading:8838784-Humans,
pubmed-meshheading:8838784-Male,
pubmed-meshheading:8838784-Myasthenia Gravis,
pubmed-meshheading:8838784-Polysomnography,
pubmed-meshheading:8838784-Prospective Studies,
pubmed-meshheading:8838784-Respiratory Function Tests,
pubmed-meshheading:8838784-Respiratory Mechanics,
pubmed-meshheading:8838784-Sleep,
pubmed-meshheading:8838784-Sleep Apnea Syndromes,
pubmed-meshheading:8838784-Wakefulness
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pubmed:year |
1995
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pubmed:articleTitle |
Breathing during sleep in myasthenia gravis.
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pubmed:affiliation |
Istituto Neurologico C. Mondino, Università di Pavia, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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