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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1996-12-3
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pubmed:abstractText |
In August and September 1993, we investigated an outbreak of legionnaires' disease in Fall River, Massachusetts, that involved 11 persons; the attack rate was highest in Flint, a community of Fall River. All cases were infected with Legionella pneumophila serogroup 1 (Lp-1). A case-control study revealed that cases were more likely than matched controls to have visited sites in neighborhood A of Flint. Environmental sampling in Flint found that four of nine aerosol-producing devices sampled contained legionellae; only two, conjoined cooling towers on building A, contained Lp-1. Three independent methods of subtyping--monoclonal antibody subtyping, arbitrary primer polymerase chain reaction, and pulsed-field gel electrophoresis--revealed that Lp-1 isolates from three cases with culture-positive legionnaires' disease matched those from the cooling towers on building A. Water samples from the homes of cases with culture-positive legionnaires' disease contained no legionellae. The results of this epidemiologic and laboratory investigation indicate that the cooling towers on building A were the source of the outbreak of legionnaires' disease and confirm the importance of cooling towers in the transmission of legionnaires' disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1058-4838
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-61
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8838181-Adult,
pubmed-meshheading:8838181-Aerosols,
pubmed-meshheading:8838181-Aged,
pubmed-meshheading:8838181-Case-Control Studies,
pubmed-meshheading:8838181-DNA, Bacterial,
pubmed-meshheading:8838181-Disease Outbreaks,
pubmed-meshheading:8838181-Disease Reservoirs,
pubmed-meshheading:8838181-Environmental Microbiology,
pubmed-meshheading:8838181-Female,
pubmed-meshheading:8838181-Humans,
pubmed-meshheading:8838181-Legionella pneumophila,
pubmed-meshheading:8838181-Legionnaires' Disease,
pubmed-meshheading:8838181-Male,
pubmed-meshheading:8838181-Massachusetts,
pubmed-meshheading:8838181-Middle Aged
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pubmed:year |
1996
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pubmed:articleTitle |
Community outbreak of Legionnaires' disease: an investigation confirming the potential for cooling towers to transmit Legionella species.
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pubmed:affiliation |
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
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pubmed:publicationType |
Journal Article
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