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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1997-1-30
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pubmed:abstractText |
Intratumoural administration of gangliosides (GSD) into a murine primitive neuro-ectodermal tumour, growing in the epicranial subcutaneous tissue of syngenic rats, results in a decrease in the tumour growth rate and causes a more differentiated phenotype of tumour cell, with immunohistochemical expression of neuronal markers. These findings suggest that the potential usefulness of intralesional administration of GSD for the control of tumours of primitive neuro-epithelial character could be considered.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-6268
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
138
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|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
759-62
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:8836294-Animals,
pubmed-meshheading:8836294-Brain,
pubmed-meshheading:8836294-Brain Neoplasms,
pubmed-meshheading:8836294-Cell Differentiation,
pubmed-meshheading:8836294-Cell Division,
pubmed-meshheading:8836294-Ethylnitrosourea,
pubmed-meshheading:8836294-Gangliosides,
pubmed-meshheading:8836294-Injections, Intralesional,
pubmed-meshheading:8836294-Neoplasm Transplantation,
pubmed-meshheading:8836294-Neuroectodermal Tumors, Primitive,
pubmed-meshheading:8836294-Phenotype,
pubmed-meshheading:8836294-Rats,
pubmed-meshheading:8836294-Rats, Wistar,
pubmed-meshheading:8836294-Tumor Cells, Cultured,
pubmed-meshheading:8836294-Tumor Markers, Biological
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pubmed:year |
1996
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pubmed:articleTitle |
Gangliosides modulate the growth rate and cell phenotype of a murine primitive neuro-ectodermal tumour.
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pubmed:affiliation |
Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, Complutensis University, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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