Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-12-4
pubmed:abstractText
The study was performed in 18 patients (15 F and 3-M) aged 35-57 yers (mean 46 +/- 7) diagnosed as idiopathic lung fibrosis. Ten patients (group A) recived standard treatment (prednisone 10-15 mg/day) and supplementary home oxygen therapy (mean 16.4 h/day) for a period of 4 years. During exacerbations antibiotics, theophylline and expectorants were prescribed. Eight patients (group B) receiving the same treatment without home oxygen, served as controls. At study entry lung function test (TLC, VL, Dlco), blood gases, hematocrit, hemodynamic parameters of the pulmonary circulation and thermodilution cardiac output were measured in all patients. The measurements were repeated after 4 years of follow-up. At follow-up examination no differences in pulmonary function parameters were shown between the groups. Mean pulmonary artery pressure and pulmonary vascular resistance were significantly lower in patients receiving home oxygen therapy (group A) as compared with those treated pharmacologically only (group B). Best effects of oxygen therapy were observed in patient with lower pulmonary artery pressures at study entry.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0032-3772
pubmed:author
pubmed:issnType
Print
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
331-6
pubmed:dateRevised
2010-4-1
pubmed:meshHeading
pubmed-meshheading:8834127-Adult, pubmed-meshheading:8834127-Anti-Inflammatory Agents, pubmed-meshheading:8834127-Blood Pressure, pubmed-meshheading:8834127-Bronchodilator Agents, pubmed-meshheading:8834127-Expectorants, pubmed-meshheading:8834127-Female, pubmed-meshheading:8834127-Follow-Up Studies, pubmed-meshheading:8834127-Home Nursing, pubmed-meshheading:8834127-Humans, pubmed-meshheading:8834127-Male, pubmed-meshheading:8834127-Middle Aged, pubmed-meshheading:8834127-Oxygen Inhalation Therapy, pubmed-meshheading:8834127-Prednisone, pubmed-meshheading:8834127-Pulmonary Artery, pubmed-meshheading:8834127-Pulmonary Circulation, pubmed-meshheading:8834127-Pulmonary Fibrosis, pubmed-meshheading:8834127-Respiratory Function Tests, pubmed-meshheading:8834127-Theophylline, pubmed-meshheading:8834127-Vascular Resistance
pubmed:year
1995
pubmed:articleTitle
[Effects of long term oxygen therapy in patients with idiopathic pulmonary fibrosis. I. Effect on the course of the primary disease and on pulmonary circulation].
pubmed:affiliation
II Katedra i Klinika Kardiologii, Slaskiej Akademii Medycznej, Zabrze.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract, Controlled Clinical Trial