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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-2-27
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pubmed:abstractText |
A patient, who was treated twice with donor lymphocyte infusions for relapse of CML after an allogeneic BMT was given lymphoblastoid human alpha-IFN after a third relapse. Further donor lymphocyte infusions were followed by repeated courses of 30 days treatment with a low dosage of IL-2 subcutaneously, alternately with alpha-IFN. This treatment resulted in a hematologic and cytogenetic remission. He also developed a limited degree of chronic GVHD. At the latest follow-up at 20 months after the third course of lymphocyte infusions he is in continuous hematologic and cytogenetic remission. Furthermore, a qualitative PCR analysis for the bcr/abl translocation is negative.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0268-3369
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-2
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8832027-Adult,
pubmed-meshheading:8832027-Bone Marrow Transplantation,
pubmed-meshheading:8832027-Combined Modality Therapy,
pubmed-meshheading:8832027-Diseases in Twins,
pubmed-meshheading:8832027-Humans,
pubmed-meshheading:8832027-Immunologic Factors,
pubmed-meshheading:8832027-Interferon-alpha,
pubmed-meshheading:8832027-Interleukin-2,
pubmed-meshheading:8832027-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:8832027-Leukemia, Myeloid, Chronic-Phase,
pubmed-meshheading:8832027-Lymphocyte Transfusion,
pubmed-meshheading:8832027-Male,
pubmed-meshheading:8832027-Neoplasm Recurrence, Local,
pubmed-meshheading:8832027-Recombinant Proteins,
pubmed-meshheading:8832027-Remission Induction,
pubmed-meshheading:8832027-Salvage Therapy,
pubmed-meshheading:8832027-Transplantation, Homologous
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pubmed:year |
1996
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pubmed:articleTitle |
Lymphoblastoid human interferon and low dose IL-2 combined with donor lymphocyte infusion as therapy of a third relapse of CML--a case report.
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pubmed:affiliation |
Department of Hematology, Huddinge Hospital, Sweden.
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pubmed:publicationType |
Journal Article,
Case Reports
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