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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
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|
pubmed:dateCreated |
1996-11-15
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|
pubmed:abstractText |
The combined effect of hormone and cytotoxic therapy on the growth of prostate cancer PC-3 in nude mice was investigated. PC-3 cell was derived from the bone metastasis of a hormone-refractory prostate cancer. Each group consisted of seven animals. After the inoculation of cancer cells, diethylstilbestrol (DES: 20 mg/kg) and futraful with uracil (UFT: 20 mg/kg) were administered for 25 days. DES and UFT synergically inhibited the growth. DES had no effect as a single agent on the growth of a hormone-independent cell line (KM20C) derived from human colon cancer. It also had no additive effect when given with UFT.
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pubmed:language |
jpn
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0385-0684
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1335-8
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:8831749-Animals,
pubmed-meshheading:8831749-Antineoplastic Agents, Hormonal,
pubmed-meshheading:8831749-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:8831749-Diethylstilbestrol,
pubmed-meshheading:8831749-Drug Combinations,
pubmed-meshheading:8831749-Drug Synergism,
pubmed-meshheading:8831749-Humans,
pubmed-meshheading:8831749-Male,
pubmed-meshheading:8831749-Mice,
pubmed-meshheading:8831749-Mice, Nude,
pubmed-meshheading:8831749-Neoplasm Transplantation,
pubmed-meshheading:8831749-Prostatic Neoplasms,
pubmed-meshheading:8831749-Tegafur,
pubmed-meshheading:8831749-Uracil
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|
pubmed:year |
1996
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|
pubmed:articleTitle |
[Inhibition of prostate cancer growth in nude mice by hormone and chemotherapy].
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|
pubmed:affiliation |
Dept. of Urology, Hamamatsu University School of Medicine.
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|
pubmed:publicationType |
Journal Article,
English Abstract
|
