Linked Life Data

8830223

Source:http://linkedlifedata.com/resource/pubmed/id/8830223

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-10-17
pubmed:abstractText
Mycobacterium ulcerans skin infection or Buruli ulcers are common in children in many rural tropical areas. The usual clinical appearance is a deep, rapidly developing chronic ulcer associated with necrosis of subcutaneous fat. Patients are usually seen at an advanced stage. Bacteriologic identification is not always possible because the pathogen, Mycobacterium ulcerans, is an atypical mycobacteria that is difficult to isolate and grows slowly in culture. Medium although of little assistance in tropical regions, the histological features are highly characteristic and can allow diagnosis in areas in which the disease is rare and unsuspected. The pathogenic effects of Mycobacterium ulcerans are due to the production of a necrotizing exotoxin with an immunosuppressive action. Treatment using antituberculosis and antileprosy drugs has been disappointing. Surgery is usually required and causes extensive sequels in many cases, the best technique being an excision/graft procedure. Many epidemiologic characteristics of Buruli ulcers which are andemic in regions with and aquatic ecosystem are still unclear including the mode of infection, transmission and reservoir. Recent outbreaks, particularly in west Africa, may be related to changes in the natural environment.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0025-682X
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
363-73
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Mycobacterium ulcerans cutaneous infections: Buruli ulcers].
pubmed:affiliation
Ministère de la Santé de la République du Bénin, Moroni, République Fédérale Islamique des Comores.
pubmed:publicationType
Journal Article, English Abstract, Review