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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1996-12-6
|
| pubmed:abstractText |
The risk of developing postoperative complications following pancreatic resection depends mainly on how difficult it is to perform a proper pancreaticointestinal anastomosis. We have evaluated the serum pancreolauryl test, a rapid tubeless pancreatic function test, as a simple preoperative predictor of the degree of pancreatic fibrosis. Degree of fibrosis in turn provides an indirect parameter for the difficulties of performing a proper and safe pancreaticointestinal anastomosis. In 35 patients (21 chronic pancreatitis, 14 pancreatic tumors) undergoing major pancreatic resection, we found a negative correlation (r = -0.75, p < 0.001) between the degree of fibrosis at the resection margin and the serum pancreolauryl test results. Patients with chronic pancreatitis had a significantly higher degree of fibrosis at the resection margin (59 +/- 22 vs. 34 +/- 25%; X +/- SD; p < 0.01) and lower fluorescein serum concentrations (2.6 +/- 1.9 vs. 4.3 +/- 2.1 micrograms/ml; X +/- SD; p < 0.01) in comparison with patients with pancreatic tumors. These findings indicate that the degree of pancreatic fibrosis, the difficulties of performing a proper pancreaticointestinal anastomosis, and subsequently the potential risk of postoperative complications can easily be predicted preoperatively.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0885-3177
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
202-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8829190-Adult,
pubmed-meshheading:8829190-Aged,
pubmed-meshheading:8829190-Bile Duct Neoplasms,
pubmed-meshheading:8829190-Chronic Disease,
pubmed-meshheading:8829190-Female,
pubmed-meshheading:8829190-Fibrosis,
pubmed-meshheading:8829190-Fluoresceins,
pubmed-meshheading:8829190-Humans,
pubmed-meshheading:8829190-Indicators and Reagents,
pubmed-meshheading:8829190-Intestinal Fistula,
pubmed-meshheading:8829190-Male,
pubmed-meshheading:8829190-Middle Aged,
pubmed-meshheading:8829190-Pancreas,
pubmed-meshheading:8829190-Pancreatic Fistula,
pubmed-meshheading:8829190-Pancreatic Neoplasms,
pubmed-meshheading:8829190-Pancreatitis,
pubmed-meshheading:8829190-Postoperative Complications,
pubmed-meshheading:8829190-Risk Factors
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
The risk of pancreaticointestinal anastomosis can be predicted preoperatively.
|
| pubmed:affiliation |
Department of Visceral and Transplantation Surgery, University of Berne, Switzerland.
|
| pubmed:publicationType |
Journal Article
|