Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1979-9-25
pubmed:abstractText
Two patients with progressive rubella panencephalitis, one with and one without stigmata of congenital rubella, were treated for 9 months with isoprinosine and showed continued clinical deterioration. Immunoviorological studies performed before, during and after treatment were unaffected by drug therapy. The virus was recovered on one occasion from the lymphocytes of one of these cases. Neither patient showed any major defects in cellular or humoral immunity. However, the lymphocytes of the patient with stigmata of congenital rubella failed to respond to rubella virus in vitro and had a heat stable, non-dialysable serum inhibitor of in vitro protein A stimulated proliferative responses. Both patients' serum interfered with the production of interferon by normal donor lymphocytes following stimulation with rubella and varicella virus antigen. Increasing serum titres of interferon which did not appear to be lymphoid or immune-specific in origin were found in these two cases.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-1016065, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-1086776, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-1117960, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-1137503, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-304871, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-4136959, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-4176269, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-4540063, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-4549192, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-47149, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-4958803, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-5334050, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-557765, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-5809842, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-70187, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-802699, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-81646, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-850076, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-890020, http://linkedlifedata.com/resource/pubmed/commentcorrection/88287-991460
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0009-9104
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
397-404
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Progressive rubella panencephalitis: immunovirological studies and results of isoprinosine therapy.
pubmed:publicationType
Journal Article