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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1996-12-3
|
| pubmed:abstractText |
To test the hypothesis that the expanded population of non-proliferative CD28-CD8+ T cells in HIV disease have shortened telomeres, thereby providing evidence that increased rounds of CD8+ cell division occur during HIV disease, possibly leading to replicative senescence and exhaustion of CD8+ T-cell responses.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0269-9370
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
F17-22
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8828735-Antigens, CD28,
pubmed-meshheading:8828735-CD8-Positive T-Lymphocytes,
pubmed-meshheading:8828735-Cell Aging,
pubmed-meshheading:8828735-Cell Division,
pubmed-meshheading:8828735-DNA,
pubmed-meshheading:8828735-HIV Infections,
pubmed-meshheading:8828735-Humans,
pubmed-meshheading:8828735-Molecular Weight,
pubmed-meshheading:8828735-T-Lymphocyte Subsets,
pubmed-meshheading:8828735-Telomere
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis.
|
| pubmed:affiliation |
Department of Pathology and Laboratory Medicine, University of California Los Angeles (UCLA) School of Medicine 90095-1745, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|