Linked Life Data

8825994

Source:http://linkedlifedata.com/resource/pubmed/id/8825994

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1996-12-3
pubmed:abstractText
Seventeen Newcastle disease virus (NDV) isolates obtained from cormorants, turkeys, a pelican, and a gull in Canada and the USA collected in 1975, 1990 and 1992 were analyzed for relatedness by monoclonal antibody profiling. In addition, nucleotide sequence analysis was performed in two areas of the fusion (F) gene for 5 of the isolates. No difference in the antigenicity of these 17 viruses, as determined by monoclonal antibody binding patterns, was seen. The amino acid sequences obtained via nucleotide sequencing at the cleavage site of the F protein showed that all the isolates tested had two pairs of basic amino acids immediately upstream of the cleavage site, and a phenylalanine residue at the N-terminus of the F1 protein, which is consistent with velogenic NDV. The deduced amino acid sequence obtained at the cleavage site of the F protein from 6 of the isolates was virtually identical regardless of the species, year of isolation, or location. However, the 1975 cormorant isolate showed marked differences from the 1990-1992 isolates in the nucleotide and deduced amino acid sequence of the F gene signal region. These data indicate that the 1990 and 1992 outbreaks were caused by the same epizootic virus and further suggest that the population of NDV in these wild birds may be very stable. The belief that the velogenic NDV circulating in cormorants in 1992 was transmitted into the free-ranging turkey flocks located near the cormorants in North Dakota is supported by the present study in which no distinction could be made between the viruses isolated from turkeys or wild birds.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-1642071, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-17424191, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-17424240, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-17648892, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-2450424, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-2647061, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-2696520, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-2705298, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-6534031, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-6838379, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-8129624, http://linkedlifedata.com/resource/pubmed/commentcorrection/8825994-8435046
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0830-9000
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
50-4
pubmed:dateRevised
2010-9-13
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Comparison of Newcastle disease viruses isolated from cormorants in Canada and the USA in 1975, 1990 and 1992.
pubmed:affiliation
Agriculture Canada, Animal Diseases Research Institute, Nepean, Ontario.
pubmed:publicationType
Journal Article, Comparative Study