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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-2-6
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pubmed:abstractText |
The strain distribution pattern of susceptibility to thymocyte apoptosis induced by ionizing radiation in 20 CcS/Dem recombinant congenic (RC) strains derived from the strains BALB/cHeA (susceptible) and STS/A (resistant) indicates that this trait is controlled by several genes. Recently, we mapped a novel apoptosis susceptibility gene Rapop1 (radiation-induced apoptosis 1) to chromosome 16 (N. Mori et al., 1995, Genomics 25: 604-614). In the present study, the analysis of F2 crosses between the resistant RC strain CcS-8 and the susceptible strain BALB/cHeA or the highly susceptible RC strain CsS-10 demonstrated two additional apoptosis susceptibility genes, Rapop2 and Rapop3, located in the proximal region of chromosome 9 and the telomeric region of chromosome 3, respectively. The possible candidate genes for these loci are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0888-7543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
553-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8825642-Analysis of Variance,
pubmed-meshheading:8825642-Animals,
pubmed-meshheading:8825642-Apoptosis,
pubmed-meshheading:8825642-Chromosome Mapping,
pubmed-meshheading:8825642-Chromosomes,
pubmed-meshheading:8825642-Female,
pubmed-meshheading:8825642-Male,
pubmed-meshheading:8825642-Mice,
pubmed-meshheading:8825642-Mice, Inbred BALB C,
pubmed-meshheading:8825642-Thymus Gland
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pubmed:year |
1995
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pubmed:articleTitle |
Apoptosis susceptibility genes on mouse chromosome 9 (Rapop2) and chromosome 3 (Rapop3).
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pubmed:affiliation |
Division of Applied Bioscience, Osaka Prefecture University, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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