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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19
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pubmed:dateCreated |
1996-11-26
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pubmed:databankReference |
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pubmed:abstractText |
Streptococcus gordonii Wicky becomes competent only after stimulation with conditioned medium from strain Challis as a source of competence factor (CF). A 3.2-kbp genomic fragment from Challis was found to impart spontaneous competence on Wicky by a complementation assay. Wicky clones containing the fragment secreted a heat-sensitive activity that induced competence in Wicky and in a comA insertion mutant of Challis. Activity was localized to a putative open reading frame, comX, with the potential to encode a 52-amino-acid peptide. comX had no similarity to known sequences, and a comX::ermAM insertion mutant of Challis transformed normally and secreted CF. These data suggest that a CF-independent pathway for competence induction exists in S. gordonii.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-13941150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-1549470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-1622271,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-1987129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-2828851,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-3009399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-3009419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-3032904,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-3127839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-3384803,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-40135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-4712569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-5018023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-5086661,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-6329717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-6934531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7479953,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7540019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7565085,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7597109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7603408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7698645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8824638-7883181
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
178
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5831-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8824638-Amino Acid Sequence,
pubmed-meshheading:8824638-Bacterial Proteins,
pubmed-meshheading:8824638-Base Sequence,
pubmed-meshheading:8824638-Culture Media, Conditioned,
pubmed-meshheading:8824638-Genetic Complementation Test,
pubmed-meshheading:8824638-Genomic Library,
pubmed-meshheading:8824638-Molecular Sequence Data,
pubmed-meshheading:8824638-Phenotype,
pubmed-meshheading:8824638-Proteins,
pubmed-meshheading:8824638-Sequence Analysis, DNA,
pubmed-meshheading:8824638-Species Specificity,
pubmed-meshheading:8824638-Streptococcus,
pubmed-meshheading:8824638-Transformation, Bacterial
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pubmed:year |
1996
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pubmed:articleTitle |
Natural genetic transformation in Streptococcus gordonii: comX imparts spontaneous competence on strain wicky.
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pubmed:affiliation |
Laboratory of Microbial Ecology, National Institute of Dental Research, Bethesda, Maryland, USA. Lunsford@yoda.nidr.nih.gov
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pubmed:publicationType |
Journal Article
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