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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1996-12-10
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pubmed:abstractText |
We have examined whether the stress-induced transcriptional activation of YDR1/PDR5/STS1 is mediated by yAP-1 and yAP-2. Of the stresses examined, heat shock-induced, rapid and transient PDR5 expression became very low in a yap1 yap2 double-gene disruptant, indicating that the yAP proteins mediate the response. Similar results were obtained with SNQ2, a close homologue of PDR5. A set of 5'-truncation derivatives of the PDR5 gene identified the region from -484 to -434 as being sufficient for the response. A sequence similar to the yAP-1 recognition element recently identified in the stress-responsive yeast genes was found in this region and in the 5'-flanking sequences of SNQ2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Protein Complex alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Vesicular...,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Fungal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PDR5 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/STS1 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/Saccharomyces cerevisiae Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/YAP1 protein, S cerevisiae
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0172-8083
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
103-5
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pubmed:dateRevised |
2009-7-24
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pubmed:meshHeading |
pubmed-meshheading:8821655-ATP-Binding Cassette Transporters,
pubmed-meshheading:8821655-Adaptor Protein Complex alpha Subunits,
pubmed-meshheading:8821655-Adaptor Proteins, Vesicular Transport,
pubmed-meshheading:8821655-Base Sequence,
pubmed-meshheading:8821655-DNA-Binding Proteins,
pubmed-meshheading:8821655-Drug Resistance, Multiple,
pubmed-meshheading:8821655-Fungal Proteins,
pubmed-meshheading:8821655-Gene Expression Regulation, Fungal,
pubmed-meshheading:8821655-Hot Temperature,
pubmed-meshheading:8821655-Membrane Proteins,
pubmed-meshheading:8821655-Molecular Sequence Data,
pubmed-meshheading:8821655-Saccharomyces cerevisiae,
pubmed-meshheading:8821655-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:8821655-Transcription, Genetic,
pubmed-meshheading:8821655-Transcription Factors
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pubmed:year |
1996
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pubmed:articleTitle |
yAP-1- and yAP-2-mediated, heat shock-induced transcriptional activation of the multidrug resistance ABC transporter genes in Saccharomyces cerevisiae.
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pubmed:affiliation |
Department of Fermentation Technology, Hiroshima University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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