Linked Life Data

8818858

Source:http://linkedlifedata.com/resource/pubmed/id/8818858

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-2-24
pubmed:abstractText
JP-8 aviation fuel is being phased in as a replacement for both JP-4 and JP-5 jet fuels presently in use by the Air Force and Navy, respectively. At the present time, 11% of active-duty Air Force personnel are women of child-bearing age. This study was undertaken to determine the threat posed to the unborn fetus should female active-duty personnel come in contact with JP-8 while pregnant. Time-mated Sprague-Dawley rats were dosed orally with JP-8 at 0, 500, 1000, 1500 and 2000 mg kg-1 day-1 on days 6-15 of pregnancy. The number and type of fetal malformations and variations observed did not differ significantly between dose groups. Dams in the 1000, 1500 and 2000 mg kg-1 day-1 groups gained significantly less body weight during pregnancy than did control dams. Embryo toxicity was indicated by a significant reduction in fetal body weight in the 1500 and 2000 mg kg-1 day-1 dose groups.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0260-437X
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-200
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Developmental toxicity of JP-8 jet fuel in the rat.
pubmed:affiliation
Comparative Medicine Branch/Armstrong Laboratory, Wright-Patterson Air Force Base, OH 45433-7902, USA.
pubmed:publicationType
Journal Article