Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8-10
|
| pubmed:dateCreated |
1997-1-7
|
| pubmed:abstractText |
A liquid chromatographic method for the analysis of ampicillin was examined in a collaborative study involving seven laboratories. The method included an isocratic part, which is used in the assay. The isocratic part is similar to the assay method for ampicillin of the US Pharmacopeia XXIII Revision. When the isocratic part is combined with gradient elution, the method is suitable for purity control. Six samples of ampicillin (anhydrous, trihydrate and sodium salt) with varying purity were analysed. The main component and related substances were determined. An analysis of variance proved the absence of consistent laboratory bias. The laboratory-sample interaction was significant. Estimates of the repeatability and reproducibility of the method, expressed as standard deviations of the result of the determination of ampicillin, were calculated to be about 0.9 and 1.1 respectively.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0731-7085
|
| pubmed:author |
pubmed-author:AletrariMM,
pubmed-author:BourkeEE,
pubmed-author:BruzziAA,
pubmed-author:FerigoWW,
pubmed-author:HoogmartensJJ,
pubmed-author:KanariPP,
pubmed-author:MillerJ HJH,
pubmed-author:MorenoM LML,
pubmed-author:NienhuisJJ,
pubmed-author:PartasidouDD,
pubmed-author:PorquerasEE,
pubmed-author:RobertJ LJL,
pubmed-author:RoetsEE,
pubmed-author:SpieserJ MJM,
pubmed-author:ZinAA
|
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1151-6
|
| pubmed:dateRevised |
2000-12-18
|
| pubmed:meshHeading | |
| pubmed:year |
1996
|
| pubmed:articleTitle |
Interlaboratory study of the analysis of ampicillin by liquid chromatography.
|
| pubmed:affiliation |
Laboratorium voor Farmaceutische Chemie en Analyse van Geneesmiddelen, Faculteit Farmaceutische Wetenschappen, Leuven, Belgium.
|
| pubmed:publicationType |
Journal Article
|