rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
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pubmed:dateCreated |
1996-10-21
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pubmed:abstractText |
The use of linear peptides as antigens for detection of serum antibodies has been studied using a sequence of the Borrelia burgdorferi protein, flagellin, and Lyme disease sera as a model. It was found that a novel presentation of the peptide as a hapten on the carrier protein, bovine serum albumin, in the enzyme-linked immunosorbent assay format can be successfully applied to distinguish between Lyme disease and control sera.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Flagellin,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin, Bovine,
http://linkedlifedata.com/resource/pubmed/chemical/Vaccines, Synthetic
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pubmed:status |
MEDLINE
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pubmed:issn |
1043-1802
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
338-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8816957-Amino Acids,
pubmed-meshheading:8816957-Animals,
pubmed-meshheading:8816957-Antibodies,
pubmed-meshheading:8816957-Antibodies, Bacterial,
pubmed-meshheading:8816957-Borrelia burgdorferi Group,
pubmed-meshheading:8816957-Cattle,
pubmed-meshheading:8816957-Chromatography, High Pressure Liquid,
pubmed-meshheading:8816957-Cysteine,
pubmed-meshheading:8816957-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:8816957-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8816957-Epitopes,
pubmed-meshheading:8816957-Flagellin,
pubmed-meshheading:8816957-Humans,
pubmed-meshheading:8816957-Lyme Disease,
pubmed-meshheading:8816957-Sensitivity and Specificity,
pubmed-meshheading:8816957-Serum Albumin, Bovine,
pubmed-meshheading:8816957-Vaccines, Synthetic
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pubmed:articleTitle |
Presentation of peptide antigens as albumin conjugates for use in detection of serum antibodies by enzyme-linked immunosorbent assay.
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pubmed:affiliation |
Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey 08854, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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