Linked Life Data

881661

Source:http://linkedlifedata.com/resource/pubmed/id/881661

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-9-17
pubmed:abstractText
Intrauterine implants made of Silastic or wax and containing various additives, including prostaglandins (PGs), were used to characterize some of the factors involved in deciduogenesis in rabbits. Implants were inserted into uteri on Day 6 of pseudopregnancy and the response was assessed by light microscopy on Day 10. The surface area of decidual tissue in histological sections was employed as an index of the degree of decidualization obtained. PGE-2, PGF-2alpha and arachidonic acid each elicited a prominent decidual response, PGE-2 being most potent. Implants which released histamine or oestradiol-17beta had a very slight decidualizing effect in some females. Control implants and implants releasing dibutyryl cyclic-AMP had no deciduogenic influence. All implants, regardless of additive content, induced a symplasmic transformation of the uterine surface epithelium. It is concluded that PGs and the distension caused by the implant may be involved in deciduogenesis in the rabbit.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-4251
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
231-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Deciduogenic effect of prostaglandins in the pseudopregnant rabbit.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.