rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1-2
|
pubmed:dateCreated |
1996-12-6
|
pubmed:abstractText |
The possible involvement of central cholinergic neurotransmission in lipomobilization in avian species was investigated by injecting carbachol into the brain lateral ventricle (i.c.v.) of conscious pigeons (N = 9 per experimental group). I.c.v. injections of carbachol (27 nmol in 1 microliter) induced an intense increase (nearly 91% above baseline levels) in the concentration of plasma free fatty acids (FFA). Previous intraperitoneal administration of hexamethonium (10 mg/kg) completely blocked the lipomobilizing effect of i.c.v. injections of carbachol. These results suggest that cholinergic neurons may be involved in central mechanisms controlling FFA mobilization in pigeons, and that this response is mainly mediated by activation of autonomic nervous system.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0165-1838
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
10
|
pubmed:volume |
59
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
83-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8816369-Acetylcholine,
pubmed-meshheading:8816369-Animals,
pubmed-meshheading:8816369-Autonomic Nervous System,
pubmed-meshheading:8816369-Carbachol,
pubmed-meshheading:8816369-Cholinergic Agonists,
pubmed-meshheading:8816369-Cholinergic Antagonists,
pubmed-meshheading:8816369-Columbidae,
pubmed-meshheading:8816369-Fatty Acids, Nonesterified,
pubmed-meshheading:8816369-Female,
pubmed-meshheading:8816369-Hexamethonium,
pubmed-meshheading:8816369-Injections, Intraventricular,
pubmed-meshheading:8816369-Lipolysis,
pubmed-meshheading:8816369-Male,
pubmed-meshheading:8816369-Synaptic Transmission
|
pubmed:year |
1996
|
pubmed:articleTitle |
Participation of the autonomic nervous system in lipolysis induced by intraventricular injection of carbachol in the pigeon.
|
pubmed:affiliation |
Department of Physiological Sciences, Center of Biological Sciences, Federal University of Santa Catarina, Brazil.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|