Linked Life Data

8816267

Source:http://linkedlifedata.com/resource/pubmed/id/8816267

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1996-11-29
pubmed:abstractText
Previous studies have shown recovery of olfactory ability along with reconnectivity of olfactory nerve (ON) following both olfactory bulb (OB) lesions and OB transplants (TX) when performed in newborn rats. The purpose of the present study is to correlate functional recovery with patterns of anatomical reconnectivity in older, postnatal (PN) 13-day-old rats (a possible critical period for plasticity in the system). Reinnervation of olfactory areas was seen in all OB TX animals regardless of the extent of functional recovery. Eight of nineteen animals with OB TXs demonstrated some degree of behavioral recovery. No reinnervation or behavioral recovery of OB lesion animals was observed. At this age, behavioral recovery is dependent upon reconnectivity within the system and transplantation may be required to facilitate this process.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
724
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
129-35
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Recovery of olfactory function in thirteen-day-old rats after olfactory bulb transplantation but not after olfactory bulb ablation.
pubmed:affiliation
Department of Neurological Surgery, University of Washington, Seattle 98195, USA.
pubmed:publicationType
Journal Article