Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-10-4
pubmed:abstractText
Electroneutral Na-(K)-Cl cotransporters are present in most cell types, where they play an important role in both sodium-chloride absorption and secretion and cell volume regulation. Recent advances in the molecular identification of these cotransporters have provided a new level of insight into the mechanisms of sodium-chloride-coupled cotransport and its regulation. Here we review what is known about the Na-(K)-Cl cotransporters cloned to date and what can be deduced about their structure and function and summarize recent physiological investigations of the regulation of Na-(K)-Cl cotransport. These studies represent the beginning of an exciting and rapidly expanding field examining the molecular mechanisms of sodium-chloride-coupled cotransport.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0066-4278
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
649-68
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Molecular mechanisms of NaCl cotransport.
pubmed:affiliation
Department of Medicine, Brigham & Women's Hospital, Massachusetts 02115, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't