Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1996-10-4
|
pubmed:abstractText |
Electroneutral Na-(K)-Cl cotransporters are present in most cell types, where they play an important role in both sodium-chloride absorption and secretion and cell volume regulation. Recent advances in the molecular identification of these cotransporters have provided a new level of insight into the mechanisms of sodium-chloride-coupled cotransport and its regulation. Here we review what is known about the Na-(K)-Cl cotransporters cloned to date and what can be deduced about their structure and function and summarize recent physiological investigations of the regulation of Na-(K)-Cl cotransport. These studies represent the beginning of an exciting and rapidly expanding field examining the molecular mechanisms of sodium-chloride-coupled cotransport.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorides,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Potassium-Chloride Symporters
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0066-4278
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
649-68
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading | |
pubmed:year |
1996
|
pubmed:articleTitle |
Molecular mechanisms of NaCl cotransport.
|
pubmed:affiliation |
Department of Medicine, Brigham & Women's Hospital, Massachusetts 02115, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|