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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1996-12-16
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pubmed:abstractText |
One hundred forty-one children with insulin-dependent diabetes mellitus were screened for serum immunoglobulin A (IgA) antigliadin antibodies by means of an enzyme-linked immunosorbent assay (ELISA) method. None of them had gastrointestinal symptoms, and no major nutritional disturbances were detected except for a girl with moderate growth delay. Twelve patients with positive IgA antigliadin antibodies on two or more consecutive measurements underwent a small intestinal biopsy; four of them had a subtotal villous atrophy, and celiac disease was diagnosed; in another patient, a partial villous atrophy was observed. Children suffering from both diabetes and celiac disease showed an onset of diabetes at a younger age than did nonceliac patients. Prevalence of celiac disease in the screened population is 2.85%, which is higher than in the general population of the Comunidad Valenciana (one in 2,500 live births).
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0277-2116
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-33
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8811520-Adolescent,
pubmed-meshheading:8811520-Biological Markers,
pubmed-meshheading:8811520-Celiac Disease,
pubmed-meshheading:8811520-Child,
pubmed-meshheading:8811520-Child, Preschool,
pubmed-meshheading:8811520-Cohort Studies,
pubmed-meshheading:8811520-Diabetes Mellitus, Type 1,
pubmed-meshheading:8811520-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8811520-Female,
pubmed-meshheading:8811520-Gliadin,
pubmed-meshheading:8811520-Humans,
pubmed-meshheading:8811520-Immunoglobulin A,
pubmed-meshheading:8811520-Incidence,
pubmed-meshheading:8811520-Male,
pubmed-meshheading:8811520-Prevalence,
pubmed-meshheading:8811520-Prospective Studies
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pubmed:year |
1996
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pubmed:articleTitle |
IgA antigliadin antibodies as a screening method for nonovert celiac disease in children with insulin-dependent diabetes mellitus.
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pubmed:affiliation |
Endocrinology and Gastroenterology Units, La Fe Children's Hospital, Valencia, Spain.
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pubmed:publicationType |
Journal Article
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