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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-2-4
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pubmed:abstractText |
Based on molecular modeling studies, a model has been proposed for intercalation of triple-helix-specific ligands (benzopyridoindole (BPI) derivatives) into triple helices, in which the intercalating compounds interact mainly with the Hoogsteen-paired strands of the triple helix. We set out to test this model experimentally using DNA duplexes capable of forming parallel Hoogsteen base-paired structures.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1074-5521
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-65
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8807829-DNA,
pubmed-meshheading:8807829-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:8807829-Hydrogen Bonding,
pubmed-meshheading:8807829-Hydrogen-Ion Concentration,
pubmed-meshheading:8807829-Ligands,
pubmed-meshheading:8807829-Nucleic Acid Conformation,
pubmed-meshheading:8807829-Nucleic Acid Denaturation,
pubmed-meshheading:8807829-Spectroscopy, Fourier Transform Infrared
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pubmed:year |
1996
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pubmed:articleTitle |
Ligand-induced formation of hoogsteen-paired parallel DNA.
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pubmed:affiliation |
Laboratoire de Biophysique, INSERM U201 CNRS URA481, Muséum National d'Histoire Naturelle, 43, rue Cuvier, 75231 Paris Cedex 05, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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