Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1996-10-22
|
pubmed:databankReference | |
pubmed:abstractText |
We established a monoclonal antibody against a surface antigen of activated macrophages (Møs) involved in the rejection of an allografted mouse tumor, Meth A. Bacteria-elicited Møs also expressed the antigen but resident or inflammatory Møs, or other leukocytes, did not. The antigen was identified as Ly-6C by isolation of cDNA clones encoding it. Two-dimensional immunoblotting revealed that Ly-6C of the Møs exists in multiple forms with a similar size but with different isoelectric points. A Ly-6C pre-mRNA also accumulated abundantly in the Møs. Thus, the multiple expression of Ly-6C and the accumulation of the pre-mRNA are the features of allograft- and bacteria-elicited Møs.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0006-291X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
4
|
pubmed:volume |
226
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
247-53
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8806622-Amino Acid Sequence,
pubmed-meshheading:8806622-Animals,
pubmed-meshheading:8806622-Antigens, Surface,
pubmed-meshheading:8806622-Blotting, Northern,
pubmed-meshheading:8806622-Cell Line,
pubmed-meshheading:8806622-DNA, Complementary,
pubmed-meshheading:8806622-Graft Rejection,
pubmed-meshheading:8806622-Macrophage Activation,
pubmed-meshheading:8806622-Male,
pubmed-meshheading:8806622-Mice,
pubmed-meshheading:8806622-Mice, Inbred BALB C,
pubmed-meshheading:8806622-Molecular Sequence Data,
pubmed-meshheading:8806622-Neoplasm Transplantation,
pubmed-meshheading:8806622-RNA, Messenger,
pubmed-meshheading:8806622-RNA Precursors,
pubmed-meshheading:8806622-Rats
|
pubmed:year |
1996
|
pubmed:articleTitle |
Multiple expression of Ly-6C and accumulation of a Ly-6C pre-mRNA in activated macrophages involved in rejection of an allografted tumor.
|
pubmed:affiliation |
Department of Cell Biology, Osaka Bioscience Institute, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|