Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-8-12
pubmed:abstractText
1. Conditions of incubation of everted sacs of rat small intestine were selected to ensure that absorption of d-glucose by mucosal tissue from the incubation medium, intracellular metabolism of the absorbed glucose and transport of glucose through the intact intestinal tissue proceeded linearly with respect to time of incubation within stated time intervals. 2. Under these experimental conditions, steady intracellular concentrations of glucose and lactate were demonstrated. 3. The quantitative translocational and metabolic fate of absorbed glucose was determined under these steady-state conditions. About 25% of glucose absorbed from the external mucosal solution was accumulated (temporarily) within mucosal tissue and about 25% transported through the intact tissue into the external serosal solution; the remainder (about 50%) of the absorbed glucose was metabolized, 90% to lactate and 10% to CO(2). Concomitant respiration rates were comparable with those reported for several other preparations of intestine and were stoicheiometrically in excess of the O(2) metabolism required to account for the production of CO(2) from the absorbed glucose. 4. Water transport through the everted sacs proceeded at an optimum rate under the experimental conditions selected. 5. Some other observations are recorded which influenced the design of the experiments and the interpretation of results; these include the initial physiological state of the animal, the anaesthetic used and the ionic composition of the incubation medium.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-1127612, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-1174558, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-1263142, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13093757, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13131249, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13131250, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13140239, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13293190, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13367043, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13426146, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13493570, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13585620, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13696270, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13762629, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13773887, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13782493, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13869151, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13869152, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-13925614, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14192544, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14203897, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14209261, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14257600, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14304214, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14343125, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-14426798, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-15406430, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4144036, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4171974, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4228176, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4235731, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4279117, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4293517, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4366460, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-4719140, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5059205, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5069299, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5070063, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5239365, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5437156, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5455646, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5557073, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5651312, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5837735, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5867297, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5867548, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5959415, http://linkedlifedata.com/resource/pubmed/commentcorrection/880223-5972154
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0264-6021
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
164
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-14
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
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