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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1996-9-27
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pubmed:abstractText |
HIV-1 subtype O is a new HIV variant originating in the West-Central African region, with highest prevalences in countries such as Cameroon, Equatorial Guinea and Gabon. Detection of antibodies to HIV-1 subtype O can pose problems in unmodified ELISA tests, and confirmation of anti-HIV-1 subtype O in immunoblot may give false negative results in some specimens. Nucleic acid-based assays designed for HIV-1 detection do not amplify or detect sequences from HIV-1 subtype O. In their env sequences, HIV-1 subtype O strains show a higher heterogeneity than the classical HIV-1 subtypes, leading to the conclusion that HIV-1 subtype O has been introduced into the human population only recently. Further, unidentified subtypes are also likely to exist.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0939-1983
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-202
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:8800800-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:8800800-Africa, Central,
pubmed-meshheading:8800800-Africa, Western,
pubmed-meshheading:8800800-Animals,
pubmed-meshheading:8800800-Biological Evolution,
pubmed-meshheading:8800800-DNA, Viral,
pubmed-meshheading:8800800-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8800800-False Negative Reactions,
pubmed-meshheading:8800800-Genes, env,
pubmed-meshheading:8800800-HIV Core Protein p24,
pubmed-meshheading:8800800-HIV-1,
pubmed-meshheading:8800800-Humans,
pubmed-meshheading:8800800-Polymerase Chain Reaction,
pubmed-meshheading:8800800-Prevalence,
pubmed-meshheading:8800800-Primates,
pubmed-meshheading:8800800-RNA, Viral
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pubmed:year |
1996
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pubmed:articleTitle |
HIV-1 subtype O: epidemiology, pathogenesis, diagnosis, and perspectives of the evolution of HIV.
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pubmed:affiliation |
Max von Pettenkofer Institute for Hygiene and Medical Microbiology, University of Munich, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Review
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