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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1997-2-20
|
| pubmed:abstractText |
Autosomal recessive (AR) polycystic kidney disease (PKD) is characterized in humans and mice as a rapidly progressive, collecting duct cystic disease usually leading to uremia in the neonatal or infantile period. In humans, ARPKD renal pathology can be variable in severity and is associated with the development of prominent bile duct and liver pathology. The C57BL/6J-cpk/cpk mouse model of ARPKD is the most extensively studied murine model of inherited infantile PKD; however, these mice lack extrarenal pathology.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0003-276X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
245
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
488-99
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:8800407-Animals,
pubmed-meshheading:8800407-Bile Ducts,
pubmed-meshheading:8800407-Crosses, Genetic,
pubmed-meshheading:8800407-Disease Models, Animal,
pubmed-meshheading:8800407-Liver,
pubmed-meshheading:8800407-Mice,
pubmed-meshheading:8800407-Mice, Inbred Strains,
pubmed-meshheading:8800407-Microscopy, Electron,
pubmed-meshheading:8800407-Microscopy, Electron, Scanning,
pubmed-meshheading:8800407-Pancreas,
pubmed-meshheading:8800407-Polycystic Kidney, Autosomal Recessive,
pubmed-meshheading:8800407-Species Specificity
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Murine autosomal recessive polycystic kidney disease with multiorgan involvement induced by the cpk gene.
|
| pubmed:affiliation |
Department of Anatomy & Cell Biology, Kansas University Kidney and Urological Research Center, Kansas City 66160-7400, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|