Linked Life Data

8799620

Source:http://linkedlifedata.com/resource/pubmed/id/8799620

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-2-11
pubmed:abstractText
This study was aimed at the identification of variations in humoral immunity parameters during the lactation period in macaque females, a recognized model in reproductive physiology and pathology. The importance of such evaluation is evidenced in particular by the central role played by the maternally transferred immunity to the progeny. The trends of serum immunoglobulins and light chains were characterized by immunonephelometry during the 6-months of lactation. The levels attained by nursing females were evaluated against a control group. The main modifications induced by lactation were in the IgM class, whose levels remained constantly lower than in the control group; the other Igs, even if showing different trends, returned to levels comparable to the control group by the end of the sixth month. Light chains quantification evidenced a significant decrease in Kappa levels; Lambda chains showed a similar trend. The variation of the Kappa/Lambda ratio was therefore minimal.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0145-305X
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
157-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Humoral immunity factors in cynomolgus macaques (Macaca fascicularis) serum: immunoglobulins and total light chains in nursing dams.
pubmed:affiliation
Laboratory of Comparative Toxicology and Ecotoxicology, Istituto Superiore di Sanità, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't