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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1996-12-3
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pubmed:abstractText |
The extent of positional variation in mucosal enzyme activity along the small intestine was investigated in 14-day-old suckling rats. Samples were taken from ten equally spaced sites along the intestine in 11 rat pups and the activities of the enzymes alkaline phosphatase, neutral aminopeptidase, gamma-glutamyl transferase, lactase and sucrase were measured. All the enzymes except sucrase were subject to considerable positional variation. Alkaline phosphatase and aminopeptidase activities were distributed throughout the intestine, with a broad maximum in the distal intestine. Lactase was also broadly distributed but with greatest activity in the mid intestine. gamma-glutamyl transferase exhibited a novel profile, with a very high proportion of the total activity (78%) present in the distal intestine. Sucrase was essentially absent throughout the intestine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Aminopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Lactase,
http://linkedlifedata.com/resource/pubmed/chemical/Sucrase,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Galactosidase,
http://linkedlifedata.com/resource/pubmed/chemical/gamma-Glutamyltransferase
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pubmed:status |
MEDLINE
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pubmed:issn |
1031-3613
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
439-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8795108-Alkaline Phosphatase,
pubmed-meshheading:8795108-Aminopeptidases,
pubmed-meshheading:8795108-Animals,
pubmed-meshheading:8795108-Animals, Suckling,
pubmed-meshheading:8795108-Intestinal Mucosa,
pubmed-meshheading:8795108-Intestine, Small,
pubmed-meshheading:8795108-Lactase,
pubmed-meshheading:8795108-Rats,
pubmed-meshheading:8795108-Rats, Inbred Strains,
pubmed-meshheading:8795108-Sucrase,
pubmed-meshheading:8795108-Time Factors,
pubmed-meshheading:8795108-beta-Galactosidase,
pubmed-meshheading:8795108-gamma-Glutamyltransferase
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pubmed:year |
1996
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pubmed:articleTitle |
Longitudinal variation in the activities of mucosal enzymes in the small intestine of suckling rats.
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pubmed:affiliation |
Clinical Research Department, Manchester Royal Infirmary, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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