Linked Life Data

8787849

Source:http://linkedlifedata.com/resource/pubmed/id/8787849

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1996-10-23
pubmed:abstractText
Like many species of teleost fish, the gymnotiform Apteronotus leptorhynchus displays a high degree of proliferative activity in a large number of brain regions during adulthood. One of these regions is the central posterior/prepacemaker nucleus (CP/PPn) in the diencephalon. By applying in situ techniques for the detection of DNA fragmentation, a feature characteristic of apoptotic cells, we show in the present study that the high proliferative activity in the CP/PPn is counterbalanced by programmed cell death. Most of the apoptotic events occur in the ventricular and subventricular zones of this thalamic complex, where the generation of the cells and their differentiation into neurons take place. The demonstration of apoptosis in the CP/PPn provides strong evidence against the hypothesis that animals in which neurogenesis continues beyond embryonic stages of development lack cell death.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
202
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Apoptosis as a regulator of cell proliferation in the central posterior/prepacemaker nucleus of adult gymnotiform fish, Apteronotus leptorhynchus.
pubmed:affiliation
Abteilung Physikalische Biologie, Max-Planck-Institut für Entwicklungsbiologie, Tübingen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't