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pubmed-article:8783940pubmed:abstractTextRecent studies have provided new insights into the molecular mechanisms by which the steroid hormone ecdysone triggers the larval-to-adult metamorphosis of Drosophila. Ecdysone-induced transcription factors activate large sets of secondary-response genes and provide the competence for subsequent regulatory responses to the hormone. It seems likely that similar hormone-triggered regulatory hierarchies exist in other higher organisms and that Drosophila is providing our first glimpses of the complexities of these gene networks.lld:pubmed
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pubmed-article:8783940pubmed:articleTitleFlies on steroids--Drosophila metamorphosis and the mechanisms of steroid hormone action.lld:pubmed
pubmed-article:8783940pubmed:affiliationHoward Hughes Medical Institute, University of Utah, Salt Lake City 84112, USA. carl.thummel@genetics.utah.edulld:pubmed
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