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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1996-10-25
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pubmed:abstractText |
Recent studies have provided new insights into the molecular mechanisms by which the steroid hormone ecdysone triggers the larval-to-adult metamorphosis of Drosophila. Ecdysone-induced transcription factors activate large sets of secondary-response genes and provide the competence for subsequent regulatory responses to the hormone. It seems likely that similar hormone-triggered regulatory hierarchies exist in other higher organisms and that Drosophila is providing our first glimpses of the complexities of these gene networks.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0168-9525
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
306-10
|
pubmed:dateRevised |
2010-4-29
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pubmed:meshHeading |
pubmed-meshheading:8783940-Animals,
pubmed-meshheading:8783940-Drosophila,
pubmed-meshheading:8783940-Ecdysone,
pubmed-meshheading:8783940-Gene Expression Regulation, Developmental,
pubmed-meshheading:8783940-Genes, Insect,
pubmed-meshheading:8783940-Insect Hormones,
pubmed-meshheading:8783940-Metamorphosis, Biological,
pubmed-meshheading:8783940-Steroids,
pubmed-meshheading:8783940-Transcription Factors
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pubmed:year |
1996
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pubmed:articleTitle |
Flies on steroids--Drosophila metamorphosis and the mechanisms of steroid hormone action.
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pubmed:affiliation |
Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112, USA. carl.thummel@genetics.utah.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|