pubmed-article:8781985 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C0001779 | lld:lifeskim |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C1123019 | lld:lifeskim |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C0242692 | lld:lifeskim |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C0123711 | lld:lifeskim |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C0013470 | lld:lifeskim |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C0021666 | lld:lifeskim |
pubmed-article:8781985 | lifeskim:mentions | umls-concept:C0443281 | lld:lifeskim |
pubmed-article:8781985 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:8781985 | pubmed:dateCreated | 1996-11-27 | lld:pubmed |
pubmed-article:8781985 | pubmed:abstractText | In female lambs aged from 2 days to 2 years, specific binding of 125I-IGF-II in muscle fibre and connective tissue of M. biceps femoris and M. gastrocnemius was demonstrated using histological autoradiography. The binding site was characterized as the IGF-II/M6P receptor in membrane preparations using competitive displacement assay and SDS-PAGE. In both muscles, 125I-IGF-II binding was more abundant in connective tissue than muscle fibre (P < or = 0.001). Levels changed significantly with age in all cell types studied (P < or = 0.001), while changes as a result of fasting were limited to a decrease in binding to the connective tissue of M. biceps femoris (P < or = 0.01). The overall decline of 125I-IGF-II binding with increasing age is correlated with a slowing of postnatal growth, while the reduction in 125I-IGF-II binding with fasting may be associated with modulating growth and composition of connective tissue, or increasing the bioavailability of IGF-II to specific muscles. | lld:pubmed |
pubmed-article:8781985 | pubmed:language | eng | lld:pubmed |
pubmed-article:8781985 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8781985 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8781985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8781985 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8781985 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8781985 | pubmed:month | Jun | lld:pubmed |
pubmed-article:8781985 | pubmed:issn | 0956-523X | lld:pubmed |
pubmed-article:8781985 | pubmed:author | pubmed-author:BassJ JJJ | lld:pubmed |
pubmed-article:8781985 | pubmed:author | pubmed-author:MartynJ AJA | lld:pubmed |
pubmed-article:8781985 | pubmed:author | pubmed-author:OldhamJ MJM | lld:pubmed |
pubmed-article:8781985 | pubmed:author | pubmed-author:NapierJ RJR | lld:pubmed |
pubmed-article:8781985 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8781985 | pubmed:volume | 6 | lld:pubmed |
pubmed-article:8781985 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8781985 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8781985 | pubmed:pagination | 88-95 | lld:pubmed |
pubmed-article:8781985 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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pubmed-article:8781985 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8781985 | pubmed:articleTitle | Postnatal age and food intake alter insulin-like growth factor-II/mannose-6-phosphate receptors in ovine skeletal muscles. | lld:pubmed |
pubmed-article:8781985 | pubmed:affiliation | AgResearch Ruakura, Hamilton, New Zealand. | lld:pubmed |
pubmed-article:8781985 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:8781985 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |