Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1976-10-20
pubmed:abstractText
beta-Endorphin, an opiate-like peptide, has potent antinociceptive properties when it is administered directly into the brain and assayed in the the tail-flick, hot-plate, and writhing tests in mice and in the wet shake test in rats. On a molar basis, beta-endorphin is 18 to 33 times more potent than morphine and its actions are blocked by the specific opiate antagonist, naloxone hydrochloride. The activity of beta-endorphin in vivo is also compared to other peptides that show opiate-like activity in assays in vitro.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1063395, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1064855, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1065904, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1094108, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1148827, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1152600, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1152601, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1171343, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1207728, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-1264229, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-13413144, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4363914, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4371024, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4411999, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4604871, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4734580, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4735025, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-4853341, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-5461245, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-5537123, http://linkedlifedata.com/resource/pubmed/commentcorrection/8780-817843
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2895-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
beta-endorphin is a potent analgesic agent.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.