| pubmed-article:8780933 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C0004114 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C0596290 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C0029005 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C0079419 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C1707520 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:8780933 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:8780933 | pubmed:issue | 5-6 | lld:pubmed |
| pubmed-article:8780933 | pubmed:dateCreated | 1997-1-21 | lld:pubmed |
| pubmed-article:8780933 | pubmed:abstractText | The aim of this report was to investigate the expression of the p53 and mdm-2 oncoproteins in astrocytic gliomas and to assess their interrelation to proliferating activities. Using monoclonal antibodies directed against p53 and mdm-2, these proteins were stained immunohistochemically in 60 astrocytic brain tumors with different histologic grade. Positive p53 stained nuclei were detected in 25.4% of the tumor cases. Mdm-2 staining products were only localized in 10.5% of specimens. Significant correlations could be found between p53, MIB-1, PCNA and mitotic index on the one hand, and tumor grade on the other hand. There were no clear relations between mdm-2 expression and proliferation markers. The grade of ploidy has a lower priority for the proliferating activity. In most cases mdm-2 immunoreactivity was strongly associated with a low or negative p53 expression. | lld:pubmed |
| pubmed-article:8780933 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8780933 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8780933 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8780933 | pubmed:month | May | lld:pubmed |
| pubmed-article:8780933 | pubmed:issn | 0947-823X | lld:pubmed |
| pubmed-article:8780933 | pubmed:author | pubmed-author:DietzmannKK | lld:pubmed |
| pubmed-article:8780933 | pubmed:author | pubmed-author:SynowitzH JHJ | lld:pubmed |
| pubmed-article:8780933 | pubmed:author | pubmed-author:von... | lld:pubmed |
| pubmed-article:8780933 | pubmed:author | pubmed-author:KircherDD | lld:pubmed |
| pubmed-article:8780933 | pubmed:author | pubmed-author:SallabaJJ | lld:pubmed |
| pubmed-article:8780933 | pubmed:author | pubmed-author:Warich-Kirche... | lld:pubmed |
| pubmed-article:8780933 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8780933 | pubmed:volume | 141 | lld:pubmed |
| pubmed-article:8780933 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8780933 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8780933 | pubmed:pagination | 339-44 | lld:pubmed |
| pubmed-article:8780933 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:meshHeading | pubmed-meshheading:8780933-... | lld:pubmed |
| pubmed-article:8780933 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8780933 | pubmed:articleTitle | Immunohistochemically detectable p53 and mdm-2 oncoprotein expression in astrocytic gliomas and their correlation to cell proliferation. | lld:pubmed |
| pubmed-article:8780933 | pubmed:affiliation | Department of Neuropathology, Medical School, Otto-von-Geuricke University of Magdeburg, Germany. | lld:pubmed |
| pubmed-article:8780933 | pubmed:publicationType | Journal Article | lld:pubmed |
