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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1996-9-19
|
| pubmed:abstractText |
Liver stellate cell proliferation and differentiation into myofibroblast-like cells is related to the development of liver fibrosis. Several cytokines, including interferons, regulate liver stellate cell proliferation and phenotypic modulation. Recent studies indicate that human liver stellate cells express the alpha-isotype of actin, specific to smooth muscle cell differentiation. We aimed to evaluate the expression of alpha-smooth muscle actin-positive liver stellate cells in patients with chronic viral hepatitis and to evaluate whether and how such expression can be modified by alpha-interferon treatment.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0168-8278
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
301-7
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8778196-Actins,
pubmed-meshheading:8778196-Adipocytes,
pubmed-meshheading:8778196-Adult,
pubmed-meshheading:8778196-Antiviral Agents,
pubmed-meshheading:8778196-Biopsy,
pubmed-meshheading:8778196-Cell Division,
pubmed-meshheading:8778196-Chronic Disease,
pubmed-meshheading:8778196-Female,
pubmed-meshheading:8778196-Hepatitis B,
pubmed-meshheading:8778196-Hepatitis C,
pubmed-meshheading:8778196-Humans,
pubmed-meshheading:8778196-Immunohistochemistry,
pubmed-meshheading:8778196-Interferon Type I,
pubmed-meshheading:8778196-Liver,
pubmed-meshheading:8778196-Male,
pubmed-meshheading:8778196-Muscle, Smooth,
pubmed-meshheading:8778196-Recombinant Proteins,
pubmed-meshheading:8778196-Treatment Outcome
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Liver stellate cells in chronic viral hepatitis: the effect of interferon therapy.
|
| pubmed:affiliation |
Cattedra di Istochimica & Immunoistochimica Patologica, Istituto di Anatomia Patologica, Università degli Studi di Padova, Italy.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|