Linked Life Data

8776875

Source:http://linkedlifedata.com/resource/pubmed/id/8776875

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-11-7
pubmed:abstractText
A linkage map of pig chromosome 6 was constructed using a wild pig/Large White intercross pedigree. The map comprises 23 polymorphic loci, and the sex-average map length is approximately 170 cM. The study adds three new genes to the chromosome 6 map: the extension (E) coat color locus, and the blood group O (EAO) and tyrosine aminotransferase (TAT) loci. Segregation at the E locus determined two coat color phenotypes among the F2 animals: wild-type color (El-) and black-spotting (Ep/Ep). The E locus showed close genetic linkage to the most distal marker (S0035) on the short arm of chromosome 6. Comparative coat color genetics as well as comparative mapping strongly suggest that E in pigs encodes the melanocyte-stimulating hormone receptor, as previously shown for the corresponding coat color loci in mouse and cattle. TAT was also mapped to the distal part of 6p, whereas EAO was the most distal marker on 6q. A clear tendency for a higher recombination rate in both terminal regions was observed. A model for the evolution of pig chromosome 6, based on comparative mapping data, is presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-1503
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
272-6
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:articleTitle
The extension coat color locus and the loci for blood group O and tyrosine aminotransferase are on pig chromosome 6.
pubmed:affiliation
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't